​We study the health and well-being of females from early adulthood to menopause with a focus on conditions and exposures that are specific to the reproductive years, such as endometriosis and hormonal-contraception use. The Safe Choice project has collected three waves of survey data on 220,000 females to improve the research foundation for studying women's health. By triangulating survey and nationwide register data, we hope to improve knowledge on the impact of transitions in female hormones and to gain insights into sex differences in health. The Safe Choice project is a collaboration between researchers at Nordsjællands Hospital, the University of Copenhagen, and the Danish Cancer Institute. The Safe Choice steering committee can be contacted at safechoice@cancer.dk.

 

The programme is funded by Sygeforsikringen "denmark". 

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Coordinators: Postdoc Amalie Lykkemark Møller and Professor Naja Hulvej Rod

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Key publications:

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• Yonis H, Løkkegaard E, Kragholm K, Granger CB, Møller AL, Mørch LS, Torp-Pedersen C, Meaidi A (2025). "Stroke and myocardial infarction with contemporary hormonal contraception: real-world, nationwide, prospective cohort study". BMJ (online) 388: e082801. Link
   

• Yonis H, Mørch LS, Løkkegaard E, Kragholm K, Møller AL, Torp-Pedersen C, Meaidi A (2025). "Contemporary hormonal contraception and risk of venous thromboembolism". JAMA : Journal of the American Medical Association. Link
   

• Skovlund CW, Møller AL, Torp-Pedersen C, Mørch LS, Meaidi A (2024). "Depression risk in users of different doses of levonorgestrel intrauterine systems: a nationwide prospective cohort study". The Lancet Regional Health–Europe 38: 100813. Link